免疫原
Synthesized peptide derived from human FAM168B
特异性
This antibody detects endogenous levels of FAM168B at Human, Mouse,Rat
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
功能
Inhibitor of neuronal axonal outgrowth. Acts as a negative regulator of CDC42 and STAT3 and a positive regulator of STMN2. Positive regulator of CDC27.
基因名称(Gene Name)
FAM168B KIAA0280L MANI
蛋白名称
Myelin-associated neurite-outgrowth inhibitor (Mani) (p20)
其他名称
FAM168B;KIAA28L;p2;Protein FAM168B;FAM168B KIAA0280L MANI;Myelin-associated neurite-outgrowth inhibitor (Mani) (p20)
细胞定位
Cytoplasm, perinuclear region . Cell membrane ; Multi-pass membrane protein . Cell projection, axon . Expressed in neuronal cell bodies and axonal fibers. .
组织表达
Expressed in the brain, within neuronal axonal fibers and associated with myelin sheets (at protein level). Expression tends to be lower in the brain of Alzheimer disease patients compared to healthy individuals (at protein level).
储存(Storage)
-15°C to -25°C/1 year(Do not lower than -25°C)