免疫原
Synthesized peptide derived from human VPS13C
特异性
This antibody detects endogenous levels of VPS13C at Human, Mouse
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
功能
Mediates the transfer of lipids between membranes at organelle contact sites (By similarity). Necessary for proper mitochondrial function and maintenance of mitochondrial transmembrane potential . Involved in the regulation of PINK1/PRKN-mediated mitophagy in response to mitochondrial depolarization .
基因名称(Gene Name)
VPS13C KIAA1421
蛋白名称
Vacuolar protein sorting-associated protein 13C
其他名称
BLTP5C;PARK23;VPS13C KIAA1421;Vacuolar protein sorting-associated protein 13C
细胞定位
Mitochondrion outer membrane . Lipid droplet . Endoplasmic reticulum membrane . Lysosome membrane . Late endosome membrane . May localize to endoplasmic reticulum-endolysosome contact sites. .
储存(Storage)
-15°C to -25°C/1 year(Do not lower than -25°C)