免疫原
Synthesized peptide derived from human SRPX2
特异性
This antibody detects endogenous levels of SRPX2 at Human, Mouse
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
功能
Acts as a ligand for the urokinase plasminogen activator surface receptor. Plays a role in angiogenesis by inducing endothelial cell migration and the formation of vascular network (cords). Involved in cellular migration and adhesion. Increases the phosphorylation levels of FAK. Interacts with and increases the mitogenic activity of HGF. Promotes synapse formation. May have a role in the perisylvian region, critical for language and cognitive development.
基因名称(Gene Name)
SRPX2 SRPUL
蛋白名称
Sushi repeat-containing protein SRPX2
其他名称
BPP;CBPS;PMGX;RESDX;SRPUL;SRPX 2;SRPX2;SRPX2_HUMAN;Sushi repeat containing protein SRPX2;Sushi repeat containing protein X linked 2;Sushi repeat protein;Sushi repeat-containing protein SRPX2;SRPX2 SRPUL
细胞定位
Secreted. Cytoplasm. Cell surface. Cell junction, synapse .
组织表达
Expressed in neurons of the rolandic area of the brain (at protein level). Highly expressed in the brain, placenta, lung, trachea, uterus, adrenal gland, heart, ovary and placenta. Weakly expressed in the peripheral blood, brain and bone marrow. Expressed in numerous cancer cell lines and in gastrointestinal cancer cells. Higher levels found in colorectal cancers than in normal colonic mucosa.
储存(Storage)
-15°C to -25°C/1 year(Do not lower than -25°C)