免疫原
Synthesized peptide derived from human SPOCD1
特异性
This antibody detects endogenous levels of SPOCD1 at Human
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
功能
Essential excecutor of PIWIL4-piRNA pathway directed transposon DNA methylation and silencing in the male embryonic germ cells (By similarity). Associates with the de novo DNA methylation machinery and repressive chromatin remodeling complexes (By similarity). Tethering of PIWIL4 to a nascent transposable element transcript recruits repressive chromatin remodeling activities and the de novo methylation apparatus through SPOCD1 (By similarity). Not required for piRNA biosynthesis (By similarity).
蛋白名称
SPOC domain-containing protein 1
其他名称
FLJ25348;RP11-84A19.1;SPOC domain-containing protein 1;SPOC1_HUMAN;SPOCD1
细胞定位
Nucleus . Chromosome .
储存(Storage)
-15°C to -25°C/1 year(Do not lower than -25°C)