免疫原
Synthesized peptide derived from human FMO2
特异性
This antibody detects endogenous levels of FMO2 at Human, Mouse,Rat
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
功能
Catalyzes the oxidative metabolism of numerous xenobiotics, including mainly therapeutic drugs and insecticides that contain a soft nucleophile, most commonly nitrogen and sulfur and participates to their bioactivation . Specifically catalyzes S-oxygenation of sulfur derived compounds such as thioureas-derived compounds, thioetherorganophosphates to their sulfenic acid . In vitro, catalyzes S-oxygenation of the second-line antitubercular drugs thiacetazone (TAZ) and ethionamide (ETA), forming a sulfinic acid and a carbodiimide via a postulated sulfenic acid intermediate . Also catalyzes S-oxygenation of the thioether-containing organophosphate insecticides, phorate and disulfoton .
蛋白名称
Dimethylaniline monooxygenase [N-oxide-forming] 2 (Dimethylaniline oxidase 2) (FMO 1B1) (Pulmonary flavin-containing monooxygenase 2) (FMO 2)
其他名称
2318D8Rik;23142I22Rik;AW17733;Dimethylaniline monooxygenase [N oxide forming] 2;Dimethylaniline monooxygenase [N-oxide-forming] 2;Dimethylaniline oxidase 2;Flavin containing monooxygenase 2 (non functional);Flavin containing monooxygenase 2;FLJ4826;FMO 1B1;FMO 2;FMO;FMO pulmonary;FMO1B1;FMO2;FMO2_HUMAN;MGC28212;OTTMUSP28686;OTTMUSP28687;Pulmonary flavin containing monooxygenase 2;Pulmonary flavin-containing monooxygenase 2;Dimethylaniline monooxygenase [N-oxide-forming] 2 (Dimethylaniline oxidase 2) (FMO 1B1) (Pulmonary flavin-containing monooxygenase 2) (FMO 2)
细胞定位
Microsome membrane ; Single-pass membrane protein . Endoplasmic reticulum membrane ; Single-pass membrane protein .
组织表达
Expressed in lung (at protein level). Expressed predominantly in lung, and at a much lesser extent in kidney. Also expressed in fetal lung, but not in liver, kidney and brain.
储存（Storage）
-15°C to -25°C/1 year(Do not lower than -25°C)
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