免疫原
Synthesized peptide derived from human EHD2
特异性
This antibody detects endogenous levels of EHD2 at Human, Mouse,Rat
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
功能
ATP- and membrane-binding protein that controls membrane reorganization/tubulation upon ATP hydrolysis (By similarity). Plays a role in membrane trafficking between the plasma membrane and endosomes . Important for the internalization of GLUT4. Required for fusion of myoblasts to skeletal muscle myotubes. Required for normal translocation of FER1L5 to the plasma membrane (By similarity). Regulates the equilibrium between cell surface-associated and cell surface-dissociated caveolae by constraining caveolae at the cell membrane .
基因名称（Gene Name）
EHD2 PAST2
蛋白名称
EH domain-containing protein 2 (PAST homolog 2)
其他名称
PAST2;EHD2;EHD2 PAST2;EH domain-containing protein 2 (PAST homolog 2)
细胞定位
Cell membrane ; Peripheral membrane protein ; Cytoplasmic side . Membrane, caveola ; Peripheral membrane protein ; Cytoplasmic side . Endosome membrane ; Peripheral membrane protein ; Cytoplasmic side . Cytoplasm, cytosol . Colocalizes with GLUT4 in intracellular tubulovesicular structures that are associated with cortical F-actin. Colocalizes with FER1L5 at plasma membrane in myoblasts and myotubes. .
组织表达
Highly expressed in heart and moderately expressed in placenta, lung, and skeletal muscle.
储存（Storage）
-15°C to -25°C/1 year(Do not lower than -25°C)
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