免疫原
Synthesized peptide derived from human ARL1
特异性
This antibody detects endogenous levels of ARL1 at Human, Mouse,Rat
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
功能
GTP-binding protein that recruits several effectors, such as golgins, arfaptins and Arf-GEFs to the trans-Golgi network, and modulates their functions at the Golgi complex . Plays thereby a role in a wide range of fundamental cellular processes, including cell polarity, innate immunity, or protein secretion mediated by arfaptins, which were shown to play a role in maintaining insulin secretion from pancreatic beta cells .
蛋白名称
ADP-ribosylation factor-like protein 1
其他名称
ARFL1;ARL1;ADP-ribosylation factor-like protein 1
细胞定位
Golgi apparatus membrane ; Peripheral membrane protein ; Cytoplasmic side . Golgi apparatus, trans-Golgi network membrane . Membrane ; Lipid-anchor .
组织表达
Detected in heart, liver, lung and liver (at protein level). Detected in fetal heart, lung, liver and kidney. Detected in adult heart, placenta, lung, liver, skeletal muscle, kidney and pancreas.
储存(Storage)
-15°C to -25°C/1 year(Do not lower than -25°C)