免疫原
Synthesized peptide derived from human LRRC32
特异性
This antibody detects endogenous levels of LRRC32 at Human
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
功能
Key regulator of transforming growth factor beta (TGFB1, TGFB2 and TGFB3) that controls TGF-beta activation by maintaining it in a latent state during storage in extracellular space . Associates specifically via disulfide bonds with the Latency-associated peptide (LAP), which is the regulatory chain of TGF-beta, and regulates integrin-dependent activation of TGF-beta . Able to outcompete LTBP1 for binding to LAP regulatory chain of TGF-beta . Controls activation of TGF-beta-1 (TGFB1) on the surface of activated regulatory T-cells (Tregs) . Required for epithelial fusion during palate development by regulating activation of TGF-beta-3 (TGFB3) (By similarity).
基因名称（Gene Name）
LRRC32 D11S833E GARP
蛋白名称
Leucine-rich repeat-containing protein 32 (Garpin) (Glycoprotein A repetitions predominant) (GARP)
其他名称
D11S833E;GARP;Garpin;LRRC32;LRRC32 D11S833E GARP;Leucine-rich repeat-containing protein 32 (Garpin) (Glycoprotein A repetitions predominant) (GARP)
细胞定位
Cell membrane ; Single-pass type I membrane protein . Cell surface .
组织表达
Preferentially expressed in regulatory T-cells (Tregs).
储存（Storage）
-15°C to -25°C/1 year(Do not lower than -25°C)
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