免疫原
Synthesized peptide derived from human C7orf43
特异性
This antibody detects endogenous levels of C7orf43 at Human, Mouse
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
功能
Specific subunit of the TRAPP (transport protein particle) II complex, a highly conserved vesicle tethering complex that functions in late Golgi trafficking as a membrane tether . TRAPP II complex has also GEF activity toward RAB1A (By similarity). TRAPPC14 is dispensable for TRAPPII complex integrity but mediates RAB3IP preciliary vesicle trafficking to the mother centriole during ciliogenesis . Modulates YAP1 activity as transcriptional regulator .
蛋白名称
Uncharacterized protein C7orf43
其他名称
C7orf43;Uncharacterized protein C7orf43
细胞定位
Cytoplasm, cytoskeleton, spindle . Vesicle . Midbody . Cytoplasm . During mitosis, precedes alpha-tubulin in gap formation of cell abscission at the midbody and is co-localized with PLK1 at the edges of microtubules extensions of daughter cells post cytokinesis abscission (PubMed:30715179). Colocalizes with RAB3IP on preciliary vesicles (PubMed:31467083). .
组织表达
Broadly expressed. High levels in brain, cerebellum, testis and whole blood.
储存（Storage）
-15°C to -25°C/1 year(Do not lower than -25°C)
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