免疫原
Synthesized peptide derived from human KIAA0528
特异性
This antibody detects endogenous levels of KIAA0528 at Human, Mouse
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
功能
Required for insulin-stimulated glucose transport and glucose transporter SLC2A4/GLUT4 translocation from intracellular glucose storage vesicle (GSV) to the plasma membrane (PM) in adipocytes. Binds phospholipid membranes in a calcium-dependent manner and is necessary for the optimal membrane fusion between SLC2A4/GLUT4 GSV and the PM.
蛋白名称
Uncharacterized protein KIAA0528
其他名称
CDP138;C2CD5;C2 domain-containing protein 5;C2 domain-containing phosphoprotein of 138 kDa;KIAA0528;Uncharacterized protein KIAA0528
细胞定位
Cytoplasmic vesicle membrane . Cytoplasm, cell cortex . Cell membrane . Cell projection, ruffle . Dynamically associated with GLUT4-containing glucose storage vesicles (GSV) and plasma membrane in response to insulin stimulation.
储存(Storage)
-15°C to -25°C/1 year(Do not lower than -25°C)