免疫原
Synthesized peptide derived from human TRIM36
特异性
This antibody detects endogenous levels of TRIM36 at Human, Mouse
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
功能
E3 ubiquitin-protein ligase which mediates ubiquitination and subsequent proteasomal degradation of target proteins. Involved in chromosome segregation and cell cycle regulation . May play a role in the acrosome reaction and fertilization.
基因名称(Gene Name)
TRIM36 RBCC728 RNF98
蛋白名称
E3 ubiquitin-protein ligase TRIM36 (RING finger protein 98) (Tripartite motif-containing protein 36) (Zinc-binding protein Rbcc728)
其他名称
TRIM36 RBCC728 RNF98;E3 ubiquitin-protein ligase TRIM36 (RING finger protein 98) (Tripartite motif-containing protein 36) (Zinc-binding protein Rbcc728)
细胞定位
Cytoplasm . Cytoplasmic vesicle, secretory vesicle, acrosome . Cytoplasm, cytoskeleton . Found in the acrosomal region of elongated spermatids and mature sperm. .
组织表达
Highly expressed in testis, prostate and brain (PubMed:15145053). Weakly expressed in kidney, lung and heart (PubMed:15145053). Expressed in fetal tissues (PubMed:28087737).
储存(Storage)
-15°C to -25°C/1 year(Do not lower than -25°C)