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科研原料 SLC7A6 Rabbit pAb

BYab-33717

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  • 货期: 3个工作日

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宿主
反应性
应用
WB
分子量(DA)
免疫原
Synthesized peptide derived from human SLC7A6
特异性
This antibody detects endogenous levels of SLC7A6 at Human, Mouse
来源
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
WB 1:500-2000
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度
1 mg/ml
背景(Background)
功能
Involved in the sodium-independent uptake of dibasic amino acids and sodium-dependent uptake of some neutral amino acids. Requires coexpression with SLC3A2/4F2hc to mediate the uptake of arginine, leucine and glutamine. Also acts as an arginine/glutamine exchanger, following an antiport mechanism for amino acid transport, influencing arginine release in exchange for extracellular amino acids. Plays a role in nitric oxide synthesis in human umbilical vein endothelial cells (HUVECs) via transport of L-arginine. Involved in the transport of L-arginine in monocytes. Reduces uptake of ornithine in retinal pigment epithelial (RPE) cells.
基因名称(Gene Name)
SLC7A6 KIAA0245
蛋白名称
Y+L amino acid transporter 2 (Cationic amino acid transporter;y+ system) (Solute carrier family 7 member 6) (y(+)L-type amino acid transporter 2) (Y+LAT2) (y+LAT-2)
简称
其他名称
KIAA0245;LAT 2;LAT3;SLC7A6;Y+L amino acid transporter 2;y+LAT 2;Y+LAT2;SLC7A6 KIAA0245;Y+L amino acid transporter 2 (Cationic amino acid transporter;y+ system) (Solute carrier family 7 member 6) (y(+)L-type amino acid transporter 2) (Y+LAT2) (y+LAT-2)
Fields
人基因ID
9057
人蛋白质序列数据库
Q92536
小鼠基因ID
330836
小鼠蛋白质序列数据库
Q8BGK6
大鼠基因ID
大鼠蛋白质序列数据库
细胞定位
Basolateral cell membrane ; Multi-pass membrane protein .
组织表达
Expressed in normal fibroblasts and those from LPI patients. Also expressed in HUVECs, monocytes, RPE cells, and various carcinoma cell lines.
储存(Storage)
-15°C to -25°C/1 year(Do not lower than -25°C)

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科研原料 SLC7A6 Rabbit pAb

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