免疫原
Synthesized peptide derived from human SEPX1
特异性
This antibody detects endogenous levels of SEPX1 at Human, Mouse,Rat
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
功能
Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases, methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post-translational modification that takes place on specific residue. Acts as a regulator of actin assembly by reducing methionine (R)-sulfoxide mediated by MICALs (MICAL1, MICAL2 or MICAL3) on actin, thereby promoting filament repolymerization. Plays a role in innate immunity by reducing oxidized actin, leading to actin repolymerization in macrophages.
基因名称(Gene Name)
MSRB1 SEPX1 HSPC270
蛋白名称
Methionine-R-sulfoxide reductase B1 (MsrB1) (Selenoprotein X) (SelX)
其他名称
HSPC27;MSRB1;Selenoprotein X;1;SELR;SELX;SEPX1;MSRB1 SEPX1 HSPC270;Methionine-R-sulfoxide reductase B1 (MsrB1) (Selenoprotein X) (SelX)
细胞定位
Cytoplasm . Nucleus . Cytoplasm, cytoskeleton .
储存(Storage)
-15°C to -25°C/1 year(Do not lower than -25°C)