免疫原
Synthesized peptide derived from human NSDHL
特异性
This antibody detects endogenous levels of NSDHL at Human, Mouse,Rat
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
功能
Catalyzes the NAD(P)(+)-dependent oxidative decarboxylation of the C4 methyl groups of 4-alpha-carboxysterols in post-squalene cholesterol biosynthesis (By similarity). Plays also a role in the regulation of the endocytic trafficking of EGFR (By similarity).
基因名称(Gene Name)
NSDHL H105E3
蛋白名称
Sterol-4-alpha-carboxylate 3-dehydrogenase;decarboxylating (Protein H105e3)
其他名称
H105E3;XAP104;SDR31E1;HL;NSDHL H105E3;Sterol-4-alpha-carboxylate 3-dehydrogenase;decarboxylating (Protein H105e3)
细胞定位
Endoplasmic reticulum membrane ; Single-pass membrane protein . Lipid droplet . Trafficking through the Golgi is necessary for ER membrane localization. .
组织表达
Brain, heart, liver, lung, kidney, skin and placenta.
储存(Storage)
-15°C to -25°C/1 year(Do not lower than -25°C)