免疫原
Synthesized peptide derived from human CKB/CKM
特异性
This antibody detects endogenous levels of CKB/CKM at Human, Mouse,Rat
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
功能
Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate) . Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa (Probable). Acts as a key regulator of adaptive thermogenesis as part of the futile creatine cycle: localizes to the mitochondria of thermogenic fat cells and acts by mediating phosphorylation of creatine to initiate a futile cycle of creatine phosphorylation and dephosphorylation (By similarity). During the futile creatine cycle, creatine and N-phosphocreatine are in a futile cycle, which dissipates the high energy charge of N-phosphocreatine as heat without performing any mechanical or chemical work (By similarity).
蛋白名称
Creatine kinase B-type (B-CK) (Creatine kinase B chain)
其他名称
CKB;KCRB;B CK;B-CK;CKBB;CKB CKBB;Creatine kinase B-type (B-CK) (Creatine kinase B chain)
细胞定位
Cytoplasm, cytosol . Mitochondrion . Localizes to the mitochondria of thermogenic fat cells via the internal MTS-like signal (iMTS-L) region. .
储存(Storage)
-15°C to -25°C/1 year(Do not lower than -25°C)