免疫原
Synthesized peptide derived from human MCRS1
特异性
This antibody detects endogenous levels of MCRS1 at Human, Mouse
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
功能
Modulates the transcription repressor activity of DAXX by recruiting it to the nucleolus . As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues . Putative regulatory component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair. May also be an inhibitor of TERT telomerase activity . Binds to G-quadruplex structures in mRNA . Binds to RNA homomer poly(G) and poly(U) .
基因名称（Gene Name）
MCRS1 INO80Q MSP58
蛋白名称
Microspherule protein 1 (58 kDa microspherule protein) (Cell cycle-regulated factor p78) (INO80 complex subunit J)
其他名称
58 kDa microspherule protein;ICP22BP;INO80 complex subunit J;INO80Q;MCRS1;MCRS2;microspherule protein 1;MSP58;P78;MCRS1 INO80Q MSP58;Microspherule protein 1 (58 kDa microspherule protein) (Cell cycle-regulated factor p78) (INO80 complex subunit J)
细胞定位
Nucleus . Nucleus, nucleolus . Cytoplasm . In microspherules in the nucleolus. .
组织表达
Detected in testis, and at lower levels in spleen, thymus, prostate, uterus, small intestine, colon and leukocytes.
储存（Storage）
-15°C to -25°C/1 year(Do not lower than -25°C)
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