免疫原
Synthesized peptide derived from human SELS
特异性
This antibody detects endogenous levels of SELS at Human, Mouse,Rat
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
功能
Involved in the degradation process of misfolded endoplasmic reticulum (ER) luminal proteins. Participates in the transfer of misfolded proteins from the ER to the cytosol, where they are destroyed by the proteasome in a ubiquitin-dependent manner. Probably acts by serving as a linker between DERL1, which mediates the retrotranslocation of misfolded proteins into the cytosol, and the ATPase complex VCP, which mediates the translocation and ubiquitination.
基因名称(Gene Name)
VIMP SELS AD-015 SBBI8
蛋白名称
Selenoprotein S (SelS) (VCP-interacting membrane protein)
其他名称
SEPS1;SELENOS;Selenoprotein S;SBBI8;ADO15;VIMP SELS AD-015 SBBI8;Selenoprotein S (SelS) (VCP-interacting membrane protein)
细胞定位
Endoplasmic reticulum membrane; Single-pass membrane protein. Cytoplasm .
储存(Storage)
-15°C to -25°C/1 year(Do not lower than -25°C)