免疫原
Synthesized peptide derived from human PSRC1
特异性
This antibody detects endogenous levels of PSRC1 at Human, Mouse,Rat
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
功能
Required for normal progression through mitosis. Required for normal congress of chromosomes at the metaphase plate, and for normal rate of chromosomal segregation during anaphase. Plays a role in the regulation of mitotic spindle dynamics. Increases the rate of turnover of microtubules on metaphase spindles, and contributes to the generation of normal tension across sister kinetochores. Recruits KIF2A and ANKRD53 to the mitotic spindle and spindle poles. May participate in p53/TP53-regulated growth suppression.
基因名称（Gene Name）
PSRC1 DDA3 FP3214
蛋白名称
Proline/serine-rich coiled-coil protein 1
其他名称
DDA3;FP3214;PSRC1;RP11 297O4.2;PSRC1 DDA3 FP3214;Proline/serine-rich coiled-coil protein 1
细胞定位
Cytoplasm. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, spindle pole. Detected at the mitotic spindle and spindle poles. Diffusely distributed throughout the cell during interphase.
组织表达
Widely expressed in adult and fetal tissues, with highest expression in the adult brain and fetal thymus. Not detected in adult skeletal muscle.
储存（Storage）
-15°C to -25°C/1 year(Do not lower than -25°C)
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