免疫原
Synthesized peptide derived from human MYDGF
特异性
This antibody detects endogenous levels of MYDGF at Human, Mouse
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
功能
Bone marrow-derived monocyte and paracrine-acting protein that promotes cardiac myocyte survival and adaptive angiogenesis for cardiac protection and/or repair after myocardial infarction (MI). Stimulates endothelial cell proliferation through a MAPK1/3-, STAT3- and CCND1-mediated signaling pathway. Inhibits cardiac myocyte apoptosis in a PI3K/AKT-dependent signaling pathway (By similarity). Involved in endothelial cell proliferation and angiogenesis .
基因名称(Gene Name)
C19orf10 IL25
蛋白名称
UPF0556 protein C19orf10 (Interleukin-25) (IL-25) (Stromal cell-derived growth factor SF20)
其他名称
C19orf10;MYDGF;Myeloid-derived growth factor;SF20;UPF0556 protein C19orf10;C19orf10 IL25;UPF0556 protein C19orf10 (Interleukin-25) (IL-25) (Stromal cell-derived growth factor SF20)
细胞定位
Secreted . Endoplasmic reticulum-Golgi intermediate compartment . Endoplasmic reticulum . Golgi apparatus . The C-terminal RTEL motif may provide retention in the endoplasmic reticulum. .
组织表达
Expressed in eosinophils (at protein level) (PubMed:29954947). Expressed in bone marrow cells (PubMed:25581518). Expressed in synovial tissue. Found in synovial fluid of patients with arthropaties (PubMed:17362502).
储存(Storage)
-15°C to -25°C/1 year(Do not lower than -25°C)