免疫原
The antiserum was produced against synthesized peptide derived from human VEGF-A. AA range: 100-200
特异性
This antibody detects endogenous levels of VEGF-A protein.
组成(Formulation)
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
稀释比例
WB 1:500-2000. IF 1:100-500. ELISA 1:1000-5000
纯化工艺(Immunogen)
Protein G
背景(Background)
This gene is a member of the PDGF/VEGF growth factor family. It encodes a heparin-binding protein, which exists as a disulfide-linked homodimer. This growth factor induces proliferation and migration of vascular endothelial cells, and is essential for both physiological and pathological angiogenesis. Disruption of this gene in mice resulted in abnormal embryonic blood vessel formation. This gene is upregulated in many known tumors and its expression is correlated with tumor stage and progression. Elevated levels of this protein are found in patients with POEMS syndrome, also known as Crow-F
蛋白名称
Vascular endothelial growth factor A
其他名称
L-VEGF;N-VEGF;Vascular Endothelial Growth Factor;vascular endothelial growth factor A;long form;VEGF-A;VEGFA
Fields
>>EGFR tyrosine kinase inhibitor resistance;>>MAPK signaling pathway;>>Ras signaling pathway;>>Rap1 signaling pathway;>>Calcium signaling pathway;>>HIF-1 signaling pathway;>>PI3K-Akt signaling pathway;>>VEGF signaling pathway;>>Focal adhesion;>>Relaxin signaling pathway;>>AGE-RAGE signaling pathway in diabetic complications;>>Human cytomegalovirus infection;>>Human papillomavirus infection;>>Kaposi sarcoma-associated herpesvirus infection;>>Pathways in cancer;>>Proteoglycans in cancer;>>MicroRNAs in cancer;>>Chemical carcinogenesis - receptor activation;>>Chemical carcinogenesis - reactive oxygen species;>>Renal cell carcinoma;>>Pancreatic cancer;>>Bladder cancer;>>Rheumatoid arthritis;>>Fluid shear stress and atherosclerosis
储存(Storage)
-15°C to -25°C/1 year(Do not lower than -25°C)