免疫原
Synthesized peptide derived from human Galectin 3 AA range: 150-250
特异性
The antibody can specifically recognize human Galectin 3 protein. In western blotting of Hela, A431 and MCF7 cell lysates, the antibody can label a 30 kDa band corresponding to Galectin 3, while there
组成（Formulation）
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
稀释比例
IHC 1:200-1000. WB 1:500-2000. IF 1:100-500. ELISA 1:1000-5000
纯化工艺（Immunogen）
Protein G
背景（Background）
Galectin-3 is a member of the β-galactose binding lectin family with a molecular weight of 30 kDa which is a chimeric structure consisting of a β-galactoside binding protein and a laminin. The main role of Galectin-3 on the cell surface is related to the adhesion between similar cells. It is expressed in a variety of organs and tissues, including neutrophils and vascular endothelial cells, but it is obviously absent in normal hepatocytes. Galectin-3 can downregulate the expression of some cancers and breast cancer associated proteins, and promote tumor metastasis. It can be used as a reference index for the degree of tumor deterioration.
功能
function:Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis.,online information:Galectin-3,simi
基因名称（Gene Name）
LGALS3 MAC2
其他名称
35 kDa lectin;Carbohydrate-binding protein 35;CBP 35;CBP35;Gal 3;Galectin-3;LGALS3 MAC2;Galectin 3;90K;90K MAC 2 BP;Basement membrane autoantigen p105;BTBD17B;Galectin 3 binding protein;Galectin-3-binding protein;L3 antigen;Lectin galactoside binding soluble 3 binding protein;Lectin galactoside-binding soluble 3-binding protein;LG3BP_HUMAN;LGALS3BP;M2BP;Mac 2 binding protein;Mac 2 BP;Mac-2 BP;Mac-2-binding protein;Mac2 BP;MAC2BP;Serum protein 90K;TANGO10B;Transport and golgi organization 10 homolog B;Tumor associated antigen 90K;Tumor-associated antigen 90K
储存（Storage）
-15°C to -25°C/1 year(Do not lower than -25°C)
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