免疫原
A synthesized peptide derived from human Phospho-TrkB (Y817)
稀释比例
WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/30
背景(Background)
The family of Trk receptor tyrosine kinases consists of TrkA, TrkB and TrkC. While the sequence of these family members is highly conserved, they are activated by different neurotrophins: TrkA by NGF, TrkB by BDNF or NT4, and TrkC by NT3. TrkA regulates proliferation and is important for development and maturation of the nervous system. Point mutations, deletions and chromosomal rearrangements (chimeras) cause ligand-independent receptor dimerization and activation of TrkA.
其他名称
AI848316;BDNF tropomyosine receptor kinase B;BDNF/NT 3 growth factors receptor;BDNF/NT-3 growth factors receptor;Brain derived neurotrophic factor receptor;C327L6Rik;EC 2.7.1.1;GP145 TrkB;GP145-TrkB;GP145-TrkB/GP95-TrkB;GP95 TrkB;Neurotrophic receptor tyrosine kinase 2;Neurotrophic tyrosine kinase receptor type 2;Neurotrophin receptor tyrosine kinase type 2;NTRK 2;Ntrk2;NTRK2_HUMAN;Obesity;hyperphagia;and developmental delay;included;RATTRKB1;Tkrb;Trk B;Trk-B;TRKB;TrkB tyrosine kinase;TRKB1;Tropomyosin related kinase B;tyrosine kinase receptor B;Tyrosine receptor kinase B;Tropomyosin-related kinase B
人基因ID
SwissProt ID
Q16620
储存(Storage)
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.