免疫原
A synthetic phosphopeptide corresponding to residues surrounding Ser473 of human AKT1
背景(Background)
Akt, also referred to as PKB or Rac, plays a critical role in controlling survival and apoptosis. This protein kinase is activated by insulin and various growth and survival factors to function in a wortmannin-sensitive pathway involving PI3 kinase. Akt is activated by phospholipid binding and activation loop phosphorylation at Thr308 by PDK1 and by phosphorylation within the carboxy terminus at Ser473.
其他名称
AKT (Ser473);p AKT;p AKT (Ser473);p-AKT;p-AKT (Ser473);AKT1; AKT1;PKB;RAC;RAC-alpha serine/threonine-protein kinase;Protein kinase B;Protein kinase B alpha;PKB alpha;Proto-oncogene c-Akt;RAC-PK-alpha
人基因ID
SwissProt ID
P31749
储存(Storage)
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.