免疫原
The antiserum was produced against synthesized peptide derived from human Chk2 around the phosphorylation site of Thr68.
稀释比例
WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200
背景(Background)
These are known to be preferred sites for phosphorylation by ATM/ATR kinases. After DNA damage by ionizing radiation (IR), UV irradiation, or hydroxyurea treatment, Thr68 and other sites in this region become phosphorylated by ATM/ATR. The SQ/TQ cluster domain, therefore, seems to have a regulatory function.
其他名称
CDS1;CHEK2;CHK2;HuCds1;LFS2;PP1425;RAD53;Serine/threonine-protein kinase Chk2;CHK2 checkpoint homolog;Cds1 homolog;hCds1;Checkpoint kinase 2
人基因ID
SwissProt ID
O96017
储存(Storage)
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.