免疫原
Synthetic peptide of human CHUK
稀释比例
WB: 1/500-1/1000 IHC: 1/50-1/100
背景（Background）
Plays an essential role in the NF-kappa-B signaling pathway which is activated by multiple stimuli such as inflammatory cytokines, bacterial or viral products, DNA damages or other cellular stresses. Activation of IKK depends upon phosphorylation at Ser177 and Ser181 in the activation loop of IKKβ (Ser176 and Ser180 in IKKα), which causes conformational changes, resulting in kinase activation.
其他名称
chuk;CHUK1;Conserved Helix Loop Helix Ubiquitous Kinase;Conserved helix loop ubiquitous kinase;Conserved helix-loop-helix ubiquitous kinase;I Kappa B Kinase 1;I Kappa B Kinase Alpha;I-kappa-B kinase 1;I-kappa-B kinase alpha;IkappaB kinase;IkB kinase alpha subunit;IkBKA;IKK 1;IKK A;IKK a kinase;IKK-A;IKK-alpha;IKK1;IKKA;IKKA_HUMAN;Inhibitor Of Kappa Light Polypeptide Gene Enhancer In B Cells;Inhibitor Of Nuclear Factor Kappa B Kinase Alpha Subunit;Inhibitor of nuclear factor kappa-B kinase subunit alpha;NFKBIKA;Nuclear Factor Kappa B Inhibitor Kinase Alpha;Nuclear factor NF kappa B inhibitor kinase alpha;Nuclear factor NF-kappa-B inhibitor kinase alpha;Nuclear factor NFkappaB inhibitor kinase alpha;Nuclear Factor Of Kappa Light Chain Gene Enhancer In B Cells Inhibitor;TCF-16;TCF16;Transcription factor 16; CHUK;Nuclear factor NF-kappa-B
人基因ID
SwissProt ID
O15111
储存（Storage）
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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