应用
WB,IPWB,IP
Cited
WB (Chicken,Drosophila)
免疫原
Recombinant protein of human JNK1
稀释比例
WB: 1/500-1/1000 IP: 1/20
背景（Background）
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli. The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis. This kinase is also involved in UV radiation induced apoptosis, which is thought to be related to cytochrom c-mediated cell death pathway. Studies of the mouse counterpart of this gene suggested that this kinase play a key role in T cell proliferation, apoptosis and differentiation. Several alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Apr 2016]
其他名称
MAPK9;c Jun N terminal kinase 2;c-Jun N-terminal kinase 2;EC:2.7.11.24;JNK 55;MAPK8;AI849689;c Jun N terminal kinase 1;C-JUN kinase 1;c-Jun N-terminal kinase 1;EC 2.7.11.24;JAK 1A;JAK1A;JNK 1;JNK 46;JNK;JNK-46;JNK1A2;JNK21B1/2;MAP kinase 8;MAPK 8;Mitogen activated protein kinase 8;Mitogen-activated protein kinase 8;MK08_HUMAN;p54 gamma;PRKM 8;PRKM8;Protein kinase JNK1;Protein kinase;mitogen-activated;8;SAPK 1;SAPK gamma;SAPK1;Stress activated protein kinase JNK1;Stress-activated protein kinase 1;Stress-activated protein kinase JNK1;Tyrosine protein kinase JAK1 .
人基因ID
SwissProt ID
P45983
储存（Storage）
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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