免疫原
Purified recombinant fragment of human SLC22A12 expressed in E. Coli.
稀释比例
WB: 1/500-1/1000 IHC: 1/100-1/200 FC: 1/50-1/100 ELISA: 1/10000
背景(Background)
The protein encoded by this gene is a member of the organic anion transporter (OAT) family, and it acts as a urate transporter to regulate urate levels in blood. This protein is an integral membrane protein primarily found in epithelial cells of the proximal tubule of the kidney. An elevated level of serum urate, hyperuricemia, is associated with increased incidences of gout, and mutations in this gene cause renal hypouricemia type 1. Alternative splicing results in multiple transcript variants.
其他名称
SLC22A12;OAT4L;OATL4;Organic anion transporter 4-like protein;Renal specific transporter;RST;URAT1
人基因ID
SwissProt ID
Q96S37
储存(Storage)
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.