免疫原
Synthesized peptide derived from human C-ternal DLDH
特异性
This antibody detects endogenous levels of DLDH at Human, Mouse,Rat
组成（Formulation）
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
稀释比例
WB 1:500-2000 IHC 1:50-200
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
功能
Lipoamide dehydrogenase is a component of the glycine cleavage system as well as an E3 component of three alpha-ketoacid dehydrogenase complexes (pyruvate-, alpha-ketoglutarate-, and branched-chain amino acid-dehydrogenase complex) . The 2-oxoglutarate dehydrogenase complex is mainly active in the mitochondrion . A fraction of the 2-oxoglutarate dehydrogenase complex also localizes in the nucleus and is required for lysine succinylation of histones: associates with KAT2A on chromatin and provides succinyl-CoA to histone succinyltransferase KAT2A . In monomeric form may have additional moonlighting function as serine protease . Involved in the hyperactivation of spermatazoa during capacitation and in the spermatazoal acrosome reaction (By similarity).
基因名称（Gene Name）
DLD GCSL LAD PHE3
蛋白名称
Dihydrolipoyl dehydrogenase;mitochondrial (EC 1.8.1.4) (Dihydrolipoamide dehydrogenase) (Glycine cleavage system L protein)
其他名称
DLDH;EC:1.8.1.4;GCSL;LAD;PHE3;DLD;DLD GCSL LAD PHE3;Dihydrolipoyl dehydrogenase;mitochondrial (EC 1.8.1.4) (Dihydrolipoamide dehydrogenase) (Glycine cleavage system L protein)
细胞定位
Mitochondrion matrix . Nucleus . Cell projection, cilium, flagellum . Cytoplasmic vesicle, secretory vesicle, acrosome . Mainly localizes in the mitochondrion. A small fraction localizes to the nucleus, where the 2-oxoglutarate dehydrogenase complex is required for histone succinylation. .
联系我们
关注我们
您当前的位置： 
说明书
成功添加到购物车
