免疫原
Synthesized peptide derived from human 14-3-3 eta
特异性
This antibody detects endogenous levels of 14-3-3 eta at Human, Mouse,Rat
组成（Formulation）
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
稀释比例
WB 1:500-2000 IHC 1:50-200
纯化工艺（Immunogen）
The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
功能
function:Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathway. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner.,similarity:Belongs to the 14-3-3 family.,subunit:Homodimer (By similarity). Interacts with many nuclear hormone receptors and cofactors including AR, ESR1, ESR2, MC2R, NR3C1, NRIP1, PPARBP and THRA. Interacts with ABL1 (phosphorylated form); the interaction retains it in the cytoplasm. Interacts with RGNEF and PCTK1 (By similarity). Weakly interacts with CDKN1B.,tissue specificity:Expressed mainly in the brain and present in other tissues albeit at lower levels.,
基因名称（Gene Name）
YWHAH YWHA1
其他名称
14 3 3 protein eta;14-3-3 eta;14-3-3 protein eta;1433F_HUMAN;Brain protein 14-3-3;eta isoform;HGNC:12853;Protein AS1;Tyrosine 3 monooxygenase/tryptophan 5 monooxygenase activation protein 1;Tyrosine 3 monooxygenase/tryptophan 5 monooxygenase activation protein eta polypeptide;Tyrosine 3 monooxygenase/tryptophan 5 monooxygenase activation protein;tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein;eta;Tyrosine 3/tryptophan 5 monooxygenase activation protein eta polypeptide;YWHA 1;YWHA1;Ywhah;PI3 Kinase P85α;YWHAH YWHA1;14-3-3 protein eta (Protein AS1)
组织表达
Expressed mainly in the brain and present in other tissues albeit at lower levels.
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