免疫原
Synthesized peptide derived from Cdk11A/B . at AA range: 190-270
特异性
Cdk11A/B Polyclonal Antibody detects endogenous levels of Cdk11A/B protein.
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景（Background）
This gene encodes a member of the serine/threonine protein kinase family. Members of this kinase family are known to be essential for eukaryotic cell cycle control. Due to a segmental duplication, this gene shares very high sequence identity with a neighboring gene. These two genes are frequently deleted or altered in neuroblastoma. The protein kinase encoded by this gene can be cleaved by caspases and may play a role in cell apoptosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015],
功能
caution:The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.,
基因名称（Gene Name）
CDK11A/CDK11B
蛋白名称
Cell division protein kinase 11A/B
其他名称
CD11A_HUMAN;CDC2L2;CDC2L3;CDK11;CDK11 p11;CDK11 p46;CDK11 p58;CDK11A;Cell division cycle 2 like 2 (PITSLRE proteins);Cell division cycle 2-like protein kinase 2;Cell division protein kinase 11A;Cyclin-dependent kinase 11A;Galactosyltransferase-associated protein kinase p58/GTA;p58GTA;PITSLRE;PITSLRE B;PITSLRE protein kinase beta;PITSLRE serine/threonine-protein kinase CDC2L2;PITSLREB;CDC2L1;Cell division cycle 2-like protein kinase 1;Cell division protein kinase 11B;CLK 1;EC=2.7.11.22;Galactosyltransferase associated protein kinase p58/GTA;ITSLRE serine/threonine protein kinase CDC2L1;p58 CLK 1;PITSLREA;PK58;Cdk11A/B;CDK11A/CDK11B;Cell division protein kinase 11A/B;PITSLRE serine/threonine-protein kinase C
组织表达
Expressed ubiquitously. Some evidence of isoform-specific tissue distribution.
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