免疫原
The antiserum was produced against synthesized peptide derived from human KCNK17. AA range:271-320
特异性
TALK-2 Polyclonal Antibody detects endogenous levels of TALK-2 protein.
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景（Background）
potassium two pore domain channel subfamily K member 17(KCNK17) Homo sapiens The protein encoded by this gene belongs to the family of potassium channel proteins containing two pore-forming P domains. This channel is an open rectifier which primarily passes outward current under physiological K+ concentrations. This gene is activated at alkaline pH. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008],
功能
function:Outward rectifying potassium channel. Produces rapidly activating and non-inactivating outward rectifier K(+) currents.,miscellaneous:Inhibited by Ba(2+), quinidine, chloroform and halothane. Activated at alkaline pH. Activated by quinine and isoflurane.,similarity:Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.,subunit:Homodimer .,
蛋白名称
Potassium channel subfamily K member 17
其他名称
2P domain potassium channel Talk 2;2P domain potassium channel Talk-2;acid sensitive potassium channel protein TASK 4;Acid-sensitive potassium channel protein TASK-4;K2p17.1;KCNK17;KCNKH_HUMAN;Potassium channel subfamily K member 17;Potassium channel;subfamily K;member 17;TALK 2;TALK-2;TALK2;TASK 4;TASK4;TWIK related acid sensitive K(+) channel 4;TWIK related alkaline pH activated K(+) channel 2;TWIK-related acid-sensitive K(+) channel 4;TWIK-related alkaline pH-activated K(+) channel 2;TWIK-related alkaline pH-activated K(+) channel
细胞定位
Membrane; Multi-pass membrane protein.
组织表达
Adrenal gland,Lung,Pancreas,Spleen,
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