免疫原
Synthesized peptide derived from Rho GDIγ . at AA range: 110-190
特异性
Rho GDIγ Polyclonal Antibody detects endogenous levels of Rho GDIγ protein.
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景（Background）
The GDP-dissociation inhibitors (GDIs) play a primary role in modulating the activation of GTPases by inhibiting the exchange of GDP for GTP. See ARHGDIB (MIM 602843).[supplied by OMIM, Nov 2010],
功能
function:Inhibits GDP/GTP exchange reaction of RhoB. Interacts specifically with the GDP- and GTP-bound forms of post-translationally processed Rhob and Rhog proteins, both of which show a growth-regulated expression in mammalian cells. Stimulates the release of the GDP-bound but not the GTP-bound RhoB protein. Also inhibits the GDP/GTP exchange of RhoB but shows less ability to inhibit the dissociation of prebound GTP.,similarity:Belongs to the Rho GDI family.,tissue specificity:Primarily expressed in pancreas and brain.,
蛋白名称
Rho GDP-dissociation inhibitor 3
其他名称
Arhgdib;D4;D4 GDP dissociation inhibitor;GDIA 2;GDIA2;GDID 4;GDID4;GDIR2_HUMAN;GDP dissociation inhibitor D4;LY GDI;Ly-GDI;LYGDI;MGC18926;RAP1GN1;Rho GDI 2;Rho GDI beta;Rho GDI2;Rho GDP dissociation inhibitor (GDI) beta;Rho GDP dissociation inhibitor 2;Rho GDP dissociation inhibitor beta;Rho GDP-dissociation inhibitor 2;Rho-GDI beta;RhoGDI2;Rho GDIγ;ARHGDIG;Rho GDP-dissociation inhibitor 3;Rho GDI 3;Rho-GDI gamma
Fields
>>Neurotrophin signaling pathway;>>Vasopressin-regulated water reabsorption
组织表达
Primarily expressed in pancreas and brain.
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