免疫原
The antiserum was produced against synthesized peptide derived from human RAD. AA range:41-90
特异性
Rad GTPase Polyclonal Antibody detects endogenous levels of Rad GTPase protein.
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景（Background）
similarity:Belongs to the small GTPase superfamily. RGK family.,subunit:Interacts with calmodulin preferentially to the inactive, GDP-form. Binds CAMKII which is capable of phosphorylating RAD in vitro.,tissue specificity:Skeletal and cardiac muscle, and lung. Lesser amounts in placenta and kidney. Also detected in adipose tissue. Overexpressed in muscle of type II diabetic humans.,
功能
similarity:Belongs to the small GTPase superfamily. RGK family.,subunit:Interacts with calmodulin preferentially to the inactive, GDP-form. Binds CAMKII which is capable of phosphorylating RAD in vitro.,tissue specificity:Skeletal and cardiac muscle, and lung. Lesser amounts in placenta and kidney. Also detected in adipose tissue. Overexpressed in muscle of type II diabetic humans.,
蛋白名称
GTP-binding protein RAD
其他名称
E311C7Rik;GD:REM;GES;GTP binding protein REM;GTP binding protein REM 1;GTP binding protein REM1;GTP-binding protein REM 1;GTPase GES;GTPase regulating endothelial cell sprouting;GTPase-regulating endothelial cell sprouting;MGC114556;MGC48669;OTTMUSP16855;Rad and Gem like GTP binding protein 1;Rad and Gem-like GTP-binding protein 1;RAS (RAD and GEM) like GTP binding;RAS like GTP binding;RAS like GTP binding protein REM;REM 1;Rem1;REM1_HUMAN;RP23-35I8.9;Rad GTPase;RRAD;GTP-binding protein RAD;RAD;RAD1;Ras associated with diabetes
组织表达
Most abundantly expressed in the heart. Also found in the skeletal muscle and lung. Lesser amounts in placenta and kidney. Also detected in adipose tissue. Overexpressed in muscle of type II diabetic humans.
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