免疫原
The antiserum was produced against synthesized peptide derived from human GNA14. AA range:1-50
特异性
Gα 14 Polyclonal Antibody detects endogenous levels of Gα 14 protein.
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景(Background)
This gene encodes a member of the guanine nucleotide-binding, or G protein family. G proteins are heterotrimers consisting of alpha, beta and gamma subunits. The encoded protein is a member of the alpha family of G proteins, more specifically the alpha q subfamily of G proteins. The encoded protein may play a role in pertussis-toxin resistant activation of phospholipase C-beta and its downstream effectors.[provided by RefSeq, Feb 2009],
功能
function:Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.,similarity:Belongs to the G-alpha family. G(q) subfamily.,subunit:G proteins are composed of 3 units; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site.,
蛋白名称
Guanine nucleotide-binding protein subunit alpha-14
其他名称
AU2328;g alpha 14;G alpha-14;G protein alpha subunit 14;G protein subunit alpha 14;G-protein subunit alpha-14;gna14;GNA14_HUMAN;Guanine nucleotide binding protein (G protein) alpha 14;Guanine nucleotide binding protein 14;Guanine nucleotide binding protein alpha 14 subunit;Guanine nucleotide binding protein subunit alpha 14;Guanine nucleotide-binding protein subunit alpha-14;MGC15546;OTTHUMP21515;Tieg3;Gα 14
Fields
>>Calcium signaling pathway;>>Chagas disease;>>Amoebiasis
细胞定位
heterotrimeric G-protein complex,plasma membrane,extracellular exosome,
组织表达
Caudate nucleus,Pancreas,Spleen,