免疫原
The antiserum was produced against synthesized peptide derived from human GROgamma. AA range:58-107
特异性
GROγ Polyclonal Antibody detects endogenous levels of GROγ protein.
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
IHC: 1/100 - 1/300. ELISA: 1/10000.. IF 1:50-200
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景（Background）
This antimicrobial gene encodes a member of the CXC subfamily of chemokines. The encoded protein is a secreted growth factor that signals through the G-protein coupled receptor, CXC receptor 2. This protein plays a role in inflammation and as a chemoattractant for neutrophils. [provided by RefSeq, Sep 2014],
功能
function:Ligand for CXCR2 (By similarity). Has chemotactic activity for neutrophils. May play a role in inflammation and exert its effects on endothelial cells in an autocrine fashion. In vitro, the processed form GRO-gamma(5-73) shows a fivefold higher chemotactic activity for neutrophilic granulocytes.,online information:CXCL3 entry,PTM:N-terminal processed form GRO-gamma(5-73) is produced by proteolytic cleavage after secretion from peripheral blood monocytes.,similarity:Belongs to the intercrine alpha (chemokine CxC) family.,
蛋白名称
C-X-C motif chemokine 3
其他名称
C-X-C motif chemokine 3;C-X-C motif chemokine ligand 3;Chemokine (C X C motif) ligand 3;Chemokine (CXC motif) ligand 3;Cinc 2;CINC 2b;Cinc2;CINC2b;CXCL 3;Cxcl3;CXCL3_HUMAN;Cytokine induced neutrophil chemoattractant 2;Dcip1;Dendritic cell inflammatory protein 1;Gm196;GRO protein gamma;GRO-gamma;GRO-gamma(1-73);GRO-gamma(5-73);GRO3;GRO3 oncogene;GROG;Growth regulated protein gamma;Growth-regulated protein gamma;Macrophage inflammatory protein 2 beta precursor;Macrophage inflammatory protein 2-beta;Melanoma growth stimulatory activity gamma;Member 3;MGSA gamma;MIP 2b;MIP2-beta;MIP2B;SCYB3;Small inducible cytokine subfamily B;GROγ
Fields
>>Cytokine-cytokine receptor interaction;>>Viral protein interaction with cytokine and cytokine receptor;>>Chemokine signaling pathway;>>NF-kappa B signaling pathway;>>NOD-like receptor signaling pathway;>>IL-17 signaling pathway;>>TNF signaling pathway;>>Alcoholic liver disease;>>Epithelial cell signaling in Helicobacter pylori infection;>>Legionellosis;>>Amoebiasis;>>Kaposi sarcoma-associated herpesvirus infection;>>Rheumatoid arthritis;>>Lipid and atherosclerosis
组织表达
Histiocytic lymphoma,Lung,Peripheral blood monocyte,Placenta,
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