免疫原
The antiserum was produced against synthesized peptide derived from human IRX3. AA range:271-320
特异性
IRX3 Polyclonal Antibody detects endogenous levels of IRX3 protein.
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
IHC: 1/100 - 1/300. ELISA: 1/20000.. IF 1:50-200
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景(Background)
IRX3 is a member of the Iroquois homeobox gene family (see IRX1; MIM 606197) and plays a role in an early step of neural development (Bellefroid et al., 1998 [PubMed 9427753]). Members of this family appear to play multiple roles during pattern formation of vertebrate embryos (Lewis et al., 1999 [PubMed 10370142]).[supplied by OMIM, Aug 2009],
功能
similarity:Belongs to the TALE/IRO homeobox family.,similarity:Contains 1 homeobox DNA-binding domain.,
蛋白名称
Iroquois-class homeodomain protein IRX-3
其他名称
IRXB3;IRX7;IRX 3;Iroquois-class homeodomain protein IRX-6;iroquois homeobox 6;IRX3;Iroquois-class homeodomain protein IRX-3;IRXB1;Homeodomain protein IRXB1;Iroquois homeobox protein 3