WB;ELISA

The antiserum was produced against synthesized peptide derived from human RSK1/2/3/4. AA range:191-240

Rsk-1/2/3/4 Polyclonal Antibody detects endogenous levels of Rsk-1/2/3/4 protein.

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

1 mg/ml

ribosomal protein S6 kinase A1(RPS6KA1) Homo sapiens This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 nonidentical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008],

catalytic activity:ATP + a protein = ADP + a phosphoprotein.,caution:The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.,cofactor:Magnesium.,enzyme regulation:Activated by multiple phosphorylations on threonine and serine residues.,function:Serine/threonine kinase that may play a role in mediating the growth-factor and stress induced activation of the transcription factor CREB.,PTM:Autophosphorylated on Ser-380, as part of the activation process.,similarity:Belongs to the protein kinase superfamily.,similarity:Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.,similarity:Contains 1 AGC-kinase C-terminal domain.,similarity:Contains 2 protein kinase domains.,subunit:Forms a complex with either ERK1 or ERK2 in quiescent cells. Transiently dissociates following mitogenic s

RPS6KA1

Ribosomal protein S6 kinase alpha-1

RSK1/2/3/4

9 kDa ribosomal protein S6 kinase 3;CLS;HU 3;HU2;HU3;Insulin stimulated protein kinase 1;Insulin-stimulated protein kinase 1;ISPK-1;ISPK1;KS6A3_HUMAN;MAP kinase activated protein kinase 1b;MAP kinase-activated protein kinase 1b;MAPK activated protein kinase 1b;MAPK-activated protein kinase 1b;MAPKAP kinase 1b;MAPKAPK 1b;MAPKAPK-1b;MAPKAPK1B;Mental retardation;X linked 19;MRX19;OTTHUMP2336;p9 RSK2;p9 RSK3;p9-RSK 3;p9RSK3;pp9RSK2;Ribosomal protein S6 kinase 9kDa polypeptide 3;Ribosomal protein S6 kinase alpha 3;Ribosomal protein S6 kinase alpha-3;Ribosomal protein s6 kinase ii alpha 2;Ribosomal S6 kinase 2;Rps6ka3;RSK;RSK-2;RSK2;S6 kinase 2;S6K alpha3;S6K-alpha-3;9 kDa ribosomal protein S6 kinase 2;HU 2;KS6A2_HUMAN;MAP kinase activated protein kinase 1c;MAP kinase-activated protein kinase 1c;MAPK-activated protein kinase 1c;MAPKAP kinase 1c;MAPKAPK-1c;MAPKAPK1C;Mitogen.activated protein kinase-activated protein kinase 1C;p9-RSK 2;p9RSK;RSK1/2/3/4;RPS6KA1;Ribosomal protein S6 kinase alpha-1;MAPKAPK1A;RSK1;S6K-alpha-1;90 kDa ribosomal protein S6 kinase 1;p90-RSK 1;p90RSK1;p90S6K;MAP kinase-activated protein kinase 1a;MAPK-activated protein kinase 1a;MAPKAP kinase 1a;MAPKAP

>>MAPK signaling pathway;>>Oocyte meiosis;>>mTOR signaling pathway;>>Thermogenesis;>>Long-term potentiation;>>Neurotrophin signaling pathway;>>Progesterone-mediated oocyte maturation;>>Insulin resistance;>>Yersinia infection;>>Chemical carcinogenesis - receptor activation

6195/6197/6196/27330

Q15418/P51812/Q15349/Q9UK32

110651/20112/67071

Nucleus. Cytoplasm.

Colon,Epithelium,

-20°C/1 year