WB;IHC;IF;ELISA

The antiserum was produced against synthesized peptide derived from human MARK1/2/3/4. AA range:181-230

MARK1/2/3/4 Polyclonal Antibody detects endogenous levels of MARK1/2/3/4 protein.

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

1 mg/ml

catalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Magnesium.,enzyme regulation:Activated by phosphorylation on Thr-215 by STK11 in complex with STE20-related adapter-alpha (STRAD alpha) pseudo kinase and CAB39.,function:May play a role in cytoskeletal stability.,similarity:Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. MARK subfamily.,similarity:Contains 1 KA1 (kinase-associated) domain.,similarity:Contains 1 protein kinase domain.,similarity:Contains 1 UBA domain.,subcellular location:Appears to localize to an intracellular network.,tissue specificity:Highly expressed in heart, skeletal muscle, brain, fetal brain and fetal kidney.,

catalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Magnesium.,enzyme regulation:Activated by phosphorylation on Thr-215 by STK11 in complex with STE20-related adapter-alpha (STRAD alpha) pseudo kinase and CAB39.,function:May play a role in cytoskeletal stability.,similarity:Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. MARK subfamily.,similarity:Contains 1 KA1 (kinase-associated) domain.,similarity:Contains 1 protein kinase domain.,similarity:Contains 1 UBA domain.,subcellular location:Appears to localize to an intracellular network.,tissue specificity:Highly expressed in heart, skeletal muscle, brain, fetal brain and fetal kidney.,

MARK1/2/3/4

Serine/threonine-protein kinase MARK1/2/3/4

MARK1/2/3/4

KIAA1477;MAP/microtubule affinity regulating kinase 1;MAP/microtubule affinity-regulating kinase 1;MARK 1;MARK;Mark1;MARK1_HUMAN;MGC126512;MGC126513;Serine/threonine protein kinase MARK1;Serine/threonine-protein kinase MARK1;ELKL motif kinase 1;ELKL motif kinase;EMK-1;EMK1;MAP/microtubule affinity regulating kinase 2;MAP/microtubule affinity-regulating kinase 2;Mark2;MARK2_HUMAN;MGC99619;PAR 1;Par 1b;PAR1 homolog;Par1b;Ser/Thr protein kinase PAR 1B;Serine/threonine protein kinase EMK;Serine/threonine protein kinase MARK2;Serine/threonine-protein kinase MARK2;C-TAK1;Cdc25C associated protein kinase 1;Cdc25C-associated protein kinase 1;cTAK1;ELKL motif kinase 2;EMK-2;Emk2;ETK 1;KIAA423;KP78;MAP microtubule affinity regulating kinase 3;MAP/microtubule affinity-regulating kinase 3;Mark3;MARK3_HUMAN;Par 1a;PAR1A;Protein kinase STK1;Ser/Thr protein kinase PAR-1;Serine threonine protein kinase p78;Serine/threonine-protein kinase p78;SerThr protein kinase PAR 1;FLJ997;KIAA186;MAP / microtubule affinity regulating kinase 4;MAP / microtubule affinity regulating kinase 4L;MAP/microtubule affinity regulating kinase 4;MAP/microtubule affinity regulating kinase like 1;MAP/microtubule affinity-regulating kinase 4;MAP/microtubule affinity-regulating kinase-like 1;MARK 4;MARK 4L;MARK L1;MARK4;MARK4 serine / threonine protein kinase;MARK4 serine/threonine protein kinase;MARK4_HUMAN;MARK4S;MARKL 1;MARKL1;Nbla65;Putative protein product of Nbla65;MARK1/2/3/4;Serine/threonine-protein kinase MARK1/2/3/4;PAR1 homolog c;Par-1c;Par1c;MAP/microtubule affin

4139/2011/4140/57787

Q9P0L2/Q7KZI7/P27448/Q96L34

226778/13728/17169/232944

117016/60328/170577

O08678/O08679/Q8VHF0

Cell membrane ; Peripheral membrane protein . Cytoplasm, cytoskeleton . Cytoplasm . Cell projection, dendrite . Appears to localize to an intracellular network. .

Highly expressed in heart, skeletal muscle, brain, fetal brain and fetal kidney.

-20°C/1 year