免疫原
The antiserum was produced against synthesized peptide derived from human GPR17. AA range:196-245
特异性
GPR17 Polyclonal Antibody detects endogenous levels of GPR17 protein.
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景（Background）
function:Dual specificity receptor for uracil nucleotides and cysteinyl leukotrienes (CysLTs). Signals through G(i) and inhibition of adenylyl cyclase. May mediate brain damage by nucleotides and CysLTs following ischemia.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Expressed in brain, kidney, heart and umbilical vein endothelial cells. Highest level in brain.,
功能
function:Dual specificity receptor for uracil nucleotides and cysteinyl leukotrienes (CysLTs). Signals through G(i) and inhibition of adenylyl cyclase. May mediate brain damage by nucleotides and CysLTs following ischemia.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Expressed in brain, kidney, heart and umbilical vein endothelial cells. Highest level in brain.,
蛋白名称
Uracil nucleotide/cysteinyl leukotriene receptor
其他名称
G protein coupled receptor 17;G-protein coupled receptor 17;P2Y like receptor;P2Y-like receptor;R12;GPR17;Uracil nucleotide/cysteinyl leukotriene receptor;UDP/CysLT receptor
细胞定位
Cell membrane; Multi-pass membrane protein.
组织表达
Expressed in brain, kidney, heart and umbilical vein endothelial cells. Highest level in brain.
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