免疫原
Purified recombinant fragment of human KLHL21 expressed in E. Coli.
特异性
KLHL21 Monoclonal Antibody detects endogenous levels of KLHL21 protein.
组成（Formulation）
Ascitic fluid containing 0.03% sodium azide,0.5% BSA, 50%glycerol.
稀释比例
WB: 1/500 - 1/2000. IHC: 1/200 - 1/1000. ELISA: 1/10000.. IF 1:50-200
纯化工艺（Immunogen）
Affinity purification
背景（Background）
function:Probable substrate-specific adapter of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.,pathway:Protein modification; protein ubiquitination.,similarity:Contains 1 BACK (BTB/Kelch associated) domain.,similarity:Contains 1 BTB (POZ) domain.,similarity:Contains 6 Kelch repeats.,subunit:Interacts with cul3.,
功能
function:Probable substrate-specific adapter of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.,pathway:Protein modification; protein ubiquitination.,similarity:Contains 1 BACK (BTB/Kelch associated) domain.,similarity:Contains 1 BTB (POZ) domain.,similarity:Contains 6 Kelch repeats.,subunit:Interacts with cul3.,
蛋白名称
Kelch-like protein 21
其他名称
kelch like 21 (Drosophila);Kelch like protein 21;KIAA0469;KLHL21;Kelch-like protein 21
细胞定位
Cytoplasm, cytoskeleton, spindle . Localizes to the spindle midzone and targets CUL3 to this region.
组织表达
Brain,Hepatoma,Hippocampus,Lung carcinoma,PCR rescued clones,Spleen,
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