免疫原
Synthesized peptide derived from human HACL1 AA range: 323-373
特异性
This antibody detects endogenous levels of HACL1 at Human/Mouse/Rat
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
功能
catalytic activity:2-hydroxyphytanoyl-CoA = pristanal + formyl-CoA.,cofactor:Binds 1 magnesium ion per subunit.,cofactor:Binds 1 thiamine pyrophosphate per subunit.,function:Catalyzes a carbon-carbon cleavage reaction; cleaves a 2-hydroxy-3-methylacyl-CoA into formyl-CoA and a 2-methyl-branched fatty aldehyde.,pathway:Lipid metabolism; fatty acid metabolism.,similarity:Belongs to the TPP enzyme family.,subunit:Homotetramer.,tissue specificity:Expressed in high levels in liver, also expressed in kidney, heart and skeletal muscle.,
基因名称(Gene Name)
HACL1 HPCL HPCL2 PHYH2 HSPC279
其他名称
2-hydroxyphytanoyl-CoA lyase;2-hydroxyacyl-CoA lyase 1;2-HPCL;2 hydroxyphytanoyl CoA lyase;2 hydroxyacyl CoA lyase 1;HACL1;HACL1 HPCL HPCL2 PHYH2 HSPC279