免疫原
Synthesized peptide derived from human JAZF1 AA range: 57-107
特异性
This antibody detects endogenous levels of JAZF1 at Human/Mouse
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
WB 1:500-2000;IHC-p 1:50-300
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
背景（Background）
This gene encodes a nuclear protein with three C2H2-type zinc fingers, and functions as a transcriptional repressor. Chromosomal aberrations involving this gene are associated with endometrial stromal tumors. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized [provided by RefSeq, Jul 2008],
功能
disease:A chromosomal aberration involving JAZF1 may be a cause of endometrial stromal tumors. Translocation t(7;17)(p15;q21) with SUZ12. The translocation generates the JAZF1-SUZ12 oncogene consisting of the N-terminus part of JAZF1 and the C-terminus part of SUZ12. It is frequently found in all cases of endometrial stromal tumors, except in endometrial stromal sarcomas, where it is rarer.,function:Potential transcription factor.,similarity:Contains 3 C2H2-type zinc fingers.,subunit:Interacts with TAK1.,
基因名称（Gene Name）
JAZF1 TIP27 ZNF802
其他名称
ChET 9 protein;CHET9;JJAZ1;Joined to JAZF1 protein;KIAA0160;JAZF1;JAZF1 TIP27 ZNF802
组织表达
Highest expression in testis with moderate levels in colon, placenta, prostate and ovary and low levels in brain, spleen, liver and small intestine.
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