免疫原
Synthesized peptide derived from human EIF3I AA range: 100-150
特异性
This antibody detects endogenous levels of EIF3I at Human/Mouse/Rat
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
功能
function:Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of posttermination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.,mass spectrometry: PubMed:17322308,mass spectrometry: PubMed:18599441,PTM:Phosphorylated by TGF-beta type II receptor.,similarity:Belongs to the eIF-3 subunit I family.,similarity:Contains 5 WD repeats.,subunit:Component of the eukaryotic
基因名称（Gene Name）
EIF3I EIF3S2 TRIP1
其他名称
Eukaryotic translation initiation factor 3 subunit 2;EIF3S2;eIF-3-beta;eIF3 p36;eIF3 beta;EIF3I;EIF3I EIF3S2 TRIP1
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