免疫原
Synthesized peptide derived from human MD12L AA range: 1848-1898
特异性
This antibody detects endogenous levels of MD12L at Human/Mouse
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
背景(Background)
The protein encoded by this gene is part of the Mediator complex, which is involved in transcriptional coactivation of nearly all RNA polymerase II-dependent genes. The Mediator complex links gene-specific transcriptional activators with the basal transcription machinery. [provided by RefSeq, May 2010],
功能
function:May be a component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.,sequence caution:Contaminating sequence. Sequence of unknown origin in the N-terminal part and potential poly-A sequence.,similarity:Belongs to the Mediator complex subunit 12 family.,subunit:May be a component of the Mediator complex, which is known to be composed of MED1, MED4, MED6, MED7, MED8, MED9, MED10, MED11, MED12, MED13, MED13L, MED14, MED15, MED16, MED17, ME
基因名称(Gene Name)
MED12L KIAA1635 TNRC11L TRALP TRALPUSH PRO0314
其他名称
MD12L;MED12L KIAA1635 TNRC11L TRALP TRALPUSH PRO0314
Fields
>>Thyroid hormone signaling pathway