免疫原
Synthesized peptide derived from human PDE6G (Phospho Thr22)
特异性
This antibody detects endogenous levels of Human, Mouse PDE6G (Phospho Thr22)
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
WB 1:1000-2000 ELISA 1:5000-20000
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
背景（Background）
This gene encodes the gamma subunit of cyclic GMP-phosphodiesterase, which is composed of alpha- and beta- catalytic subunits and two identical, inhibitory gamma subunits. This gene is expressed in rod photoreceptors and functions in the phototransduction signaling cascade. It is also expressed in a variety of other tissues, and has been shown to regulate the c-Src protein kinase and G-protein-coupled receptor kinase 2. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2009],
功能
catalytic activity:Guanosine 3',5'-cyclic phosphate + H(2)O = guanosine 5'-phosphate.,function:Participates in processes of transmission and amplification of the visual signal. cGMP-PDEs are the effector molecules in G-protein-mediated phototransduction in vertebrate rods and cones.,online information:Retina International's Scientific Newsletter,similarity:Belongs to the rod/cone cGMP-PDE gamma subunit family.,subunit:Oligomer composed of two catalytic chains (alpha and beta), an inhibitory chain (gamma) and the delta chain.,
基因名称（Gene Name）
PDE6G PDEG
蛋白名称
PDE6G (Phospho Thr22)
其他名称
5''-cyclic phosphodiesterase subunit gamma;CNRG_HUMAN;GMP-PDE gamma;MGC125749;PDE 6;PDE6G;PDEG;Phosphodiesterase 6G cGMP Specific;Phosphodiesterase 6G cGMP specific rog gamma;Retinal Rod Photoreceptor cGMP Phosphodiesterase gamma;Retinal rod rhodopsin sensitive cGMP 3' 5'vcyclic phosphodiesterase subunit gamma;Retinal rod rhodopsin-sensitive cGMP 3'';Rod cG PDE G;RP57;PDE6G PDEG;PDE6G (Phospho Thr22);Retinal rod rhodopsin-sensitive cGMP 3';5'-cyclic phosphodiesterase subunit gamma (GMP-PDE gamma;EC 3.1.4.35)
Fields
>>Purine metabolism;>>Metabolic pathways;>>Phototransduction
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