免疫原
Synthesized peptide derived from human AMPL AA range: 332-382
特异性
This antibody detects endogenous levels of AMPL at Human/Mouse/Rat
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
功能
catalytic activity:Release of an N-terminal amino acid, Xaa-|-Yaa-, in which Xaa is preferably Leu, but may be other amino acids including Pro although not Arg or Lys, and Yaa may be Pro. Amino acid amides and methyl esters are also readily hydrolyzed, but rates on arylamides are exceedingly low.,catalytic activity:Release of N-terminal proline from a peptide.,cofactor:Binds 2 zinc ions per subunit. One zinc ion is tightly bound and essential for enzyme activity, while the second metal coordination site can be occupied by zinc, magnesium or manganese to give enzymes of different activities.,function:Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.,similarity:Belongs to the peptidase M17 family.,subunit:Homohexamer.,
基因名称(Gene Name)
LAP3 LAPEP PEPS
其他名称
ACTR;AIB 1;AIB-1;AIB1;Amplified in breast cancer 1;Amplified in breast cancer 1 protein;bHLHe42;CAGH 16;CAGH16;CBP interacting protein;CBP-interacting protein;Class E basic helix-loop-helix protein 42;CTG 26;CTG26;KAT13B / AIB1;MGC141848;NCOA 3;NCoA-3;Ncoa3;NCOA3_HUMAN;Nuclear receptor coactivator 3;pCIP;RAC 3;RAC-3;RAC3;Receptor associated coactivator 3;Receptor-associated coactivator 3;SRC 3;SRC-3;SRC3;Steroid receptor coactivator protein 3;Thyroid hormone receptor activator molecule 1;TNRC14;TNRC16;TRAM 1;TRAM-1;TRAM1;AMPL;LAP3 LAPEP PEPS
Fields
>>Arginine and proline metabolism;>>Glutathione metabolism;>>Metabolic pathways