免疫原
Synthesized peptide derived from human HP1B3 AA range: 283-333
特异性
This antibody detects endogenous levels of HP1B3 at Human/Mouse/Rat
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
功能
function:Component of heterochromatin, may be involved in chromatin structure and function.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the histone H1/H5 family.,similarity:In the C-terminal section; belongs to the histone H1/H5 family.,subunit:Interacts with CBX5.,
其他名称
Heterochromatin protein 1;binding protein 3;Heterochromatin protein 1-binding protein 3;HP1 BP74;HP1B3_HUMAN;HP1BP 3;HP1BP3;MGC28927;MGC4371;MGC72624;OTTHUMP2717;OTTHUMP2719;OTTHUMP272;Protein HP1 BP74;Protein HP1-BP74;RP5 93J4.3;HP1B3
细胞定位
Nucleus . Chromosome . localized in nuclei but not in nucleoli in interphase. Colocalized with chromosomes in mitosis, with a gradually increased during G1 progression and a maximum level during late G1 phase (G1/S). .