免疫原
Synthesized peptide derived from human UBR3 AA range: 1591-1641
特异性
This antibody detects endogenous levels of UBR3 at Human/Mouse
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
功能
function:E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. Does not bind to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.,pathway:Protein modification; protein ubiquitination.,sequence caution:Translated as Gln.,similarity:Belongs to the UBR1 family.,similarity:Contains 1 RING-type zinc finger.,similarity:Contains 1 UBR-type zinc finger.,subunit:Interacts with UBE2A and UBE2B.,
基因名称（Gene Name）
UBR3 KIAA2024 ZNF650
其他名称
bA49A4.1;C6orf133;dJ242G1.1;dJ392M17.3;DKFZp686C8114;E3 ubiquitin protein ligase UBR2;KIAA349;MGC71112;N recognin 2;OTTHUMP1643;OTTHUMP39767;OTTHUMP39768;RP3 392M17.3;Ubiquitin ligase E3 alpha II;Ubiquitin protein ligase E3 alpha 2;Ubiquitin protein ligase E3 alpha II;Ubiquitin protein ligase E3 component n recognin 2;UBR 2;UBR3;UBR3 KIAA2024 ZNF650
细胞定位
Membrane ; Multi-pass membrane protein .
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