免疫原
Synthesized peptide derived from human DPYL3 AA range: 240-290
特异性
This antibody detects endogenous levels of DPYL3 at Human/Mouse/Rat
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.179% sodium azide.
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
功能
function:Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, neuronal growth cone collapse and cell migration.,similarity:Belongs to the DHOase family. Hydantoinase/dihydropyrimidinase subfamily.,subcellular location:Colocalizes with synaptic vesicle protein 2 in the central region of the growth cone.,subunit:Homotetramer, and heterotetramer with CRMP1, DPYSL2, DPYSL4 or DPYSL5 (By similarity). Interacts with synaptic vesicle protein 2 and SH3A domain of intersectin.,tissue specificity:Mainly in heart and skeletal muscle. Also expressed strongly in fetal brain and spinal cord.,
基因名称（Gene Name）
DPYSL3 CRMP4 DRP3 ULIP ULIP1
其他名称
Collapsin response mediator protein 4;Collapsin response mediator protein 4 long;CRMP 4;CRMP-4;CRMP4;Dihydropyrimidinase like 3;Dihydropyrimidinase related protein 3;Dihydropyrimidinase-related protein 3;DPYL3_HUMAN;DPYSL3;DRP 3;DRP-3;DRP3;LCRMP;TUC4;ULIP 1;ULIP;ULIP-1;ULIP1;UNc 33 like phosphoprotein 1;Unc 33 like phosphoprotein;Unc-33-like phosphoprotein 1;DPYL3;DPYSL3 CRMP4 DRP3 ULIP ULIP1;Dihydropyrimidinase-related protein 3 (DRP-3) (Collapsin response mediator protein 4) (CRMP-4) (Unc-33-like phosphoprotein 1) (ULIP-1)
细胞定位
Cytoplasm . Cell projection, growth cone . Colocalizes with synaptic vesicle protein 2 in the central region of the growth cone. .
组织表达
Mainly expressed in heart and skeletal muscle. Also strongly expressed in fetal brain and spinal cord.
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