免疫原
Synthesized peptide derived from human CR1L AA range: 45-95
特异性
This antibody detects endogenous levels of CR1L at Human/Mouse/Rat
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.163% sodium azide.
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
功能
similarity:Belongs to the receptors of complement activation (RCA) family.,similarity:Contains 8 Sushi (CCP/SCR) domains.,subcellular location:Predominantly found in association with the membrane fraction, but also located in the cytoplasm and in the supernatant.,subunit:Interacts with iC4 (methylamine-treated C4) but not for iC3 (methylamine-treated C3).,tissue specificity:Expressed in fetal liver and to a lesser extent in fetal spleen and thymus. Expression appears to be limited to hematopoietic and fetal lymphoid tissue.,
其他名称
C C chemokine receptor type 2;C C CKR 2;C-C chemokine receptor type 2;C-C CKR-2;CC chemokine receptor type 2;CC CKR 2;CC-CKR-2;CCCKR2;CCR 2;CCR-2;CCR1L;CCR2;CCR2_HUMAN;CCR2A;CCR2B;CCR5L;CD192;CD192 antigen;Chemokine C C motif receptor 2;Chemokine CC Motif Receptor 2;CKR 2;CKR2;CKR2A;CKR2B;CMKBR2;MCP 1 R;MCP-1-R;MCP1 RECEPTOR;MCP1R;Monocyte chemoattractant protein 1 receptor;Monocyte Chemotactic Protein 1 Receptor;CR1L;Complement component receptor 1-like protein (Complement C4b-binding protein CR-1-like protein)
Fields
>>Complement and coagulation cascades;>>Neutrophil extracellular trap formation;>>Hematopoietic cell lineage;>>Legionellosis;>>Leishmaniasis;>>Malaria;>>Tuberculosis
细胞定位
Cytoplasm . Membrane . Secreted . Predominantly found in association with the membrane fraction, but also located in the cytoplasm and in the supernatant.
组织表达
Expressed in fetal liver and to a lesser extent in fetal spleen and thymus. Expression appears to be limited to hematopoietic and fetal lymphoid tissue.
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